DOPAMINE INJ

Description

Dopamine Injection is a catecholamine and endogenous neurotransmitter that acts on dopaminergic, beta-adrenergic, and alpha-adrenergic receptors in a dose-dependent manner. At low doses (2–5 mcg/kg/min), it causes renal and mesenteric vasodilation; at intermediate doses (5–10 mcg/kg/min), it exerts positive inotropic and chronotropic effects via beta-1 stimulation; and at high doses (>10 mcg/kg/min), alpha-adrenergic vasoconstriction predominates, raising systemic vascular resistance. It is used in the management of hemodynamic instability, cardiogenic shock, septic shock, and acute heart failure where vasopressor or inotropic support is required. It must be administered via central venous access due to the risk of severe tissue necrosis upon extravasation.