Glucophage (Metformin HCI

Description

Glucophage (Metformin HCl) is a first-line oral biguanide antidiabetic medication widely prescribed for the management of type 2 diabetes mellitus, particularly in overweight and obese patients. It works primarily by reducing hepatic glucose production, decreasing intestinal glucose absorption, and improving peripheral insulin sensitivity, without stimulating insulin secretion, thus carrying a low risk of hypoglycemia. Available in various strengths, it effectively lowers fasting and postprandial blood glucose levels and HbA1c, while also offering additional benefits such as modest weight reduction and cardiovascular protection. It is often used as monotherapy or in combination with other antidiabetic agents when glycemic targets are not achieved with diet and exercise alone.